Hair Loss Drugs - Database of Drugs for Hair Loss

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Hair Loss Drugs

Reductase Inhibitors

FCE - dual inhibitors
FCE 28260
FCE 28175
FCE 27837

MK Inhibitors
MK 0434
MK 0963
MK 386

FK Nonsteroidal Inhibitors
FK 143

LY Nonsteroidal Inhibitors
LY 191704

SK&F Inhibitors
SK&F 105657

Dutasteride (Avodart, GI198745)

Finasteride (Propecia, Proscar)

Turosteride

Azelaic acid

Zinc sulphate

CS 891

AntiAndrogens

Spironolactone (Aldactone)

Flutamide (Euflex, Eulexin)

Casodex

Inocoterone

RU Antiandrogens

TZP-4238

Win 49596

Fluridil (Eucapil)

K+ Channel Openers

Rogaine (Minoxidil)

Diazoxide

Cromakalim

Pinacidil

Estrogen Blockers

ICI Estrogen Blocker

FCE 28260 - dual 5-alpha reductase inhibitor.

Novel 4-azasteroid, dual 5-alpha reductase (type 1 and 2 isozymes) inhibitor with steroid structure (azasteroid). Not an antiandrogen.

Mechanism:
FCE 28260, reversibly inhibit 5 alpha-red...click for details

FCE 28175 - competative 5a-reductase inhibitor.

Novel 4-azasteroid, dual 5-alpha reductase (type 1 and 2 isozymes) inhibitor with steroid structure (azasteroid). Not an antiandrogen.

Mechanism:
FCE 28175, reversibly inhibit 5 alpha-red...click for details

FCE 27837 - dual 5a-reductase inhibitor.

Novel 4-azasteroid, dual 5-alpha reductase (type 1 and 2 isozymes) inhibitor with steroid structure (azasteroid). Not an antiandrogen.

Mechanism:
FCE 27837, reversibly inhibit 5 alpha-red...click for details

FK 143 - nonsteroidal selective 5 alpha-reductase inhibitor.

New nonsteroidal selective 5 alpha-reductase inhibitor.

Mechanism:
FK143 inhibited human and rat 5 alpha-reductases (preferably type 1 isoenzyme) in a noncompetitive fashion (opposed to ...click for details

MK 0434 - 5a-reductase inhibitor with steroid structure.

Novel 4-azasteroid, 5-alpha reductase inhibitor with steroid structure (azasteroid). Not an antiandrogen.

Mechanism:
MK 0434, reversibly inhibit 5 alpha-reductase in competitive mode, resu...click for details

MK 0963 5a-reductase inhibitor with steroid structure.

Novel 4-azasteroid, 5-alpha reductase inhibitor with steroid structure (azasteroid). Not an antiandrogen.

Mechanism:
MK 0963, reversibly inhibit 5 alpha-reductase in competitive mode, res...click for details

MK 386 - steroid type 1 of 5a-reductase selective inhibitor.

Novel 4-azasteroid, type 1 of 5-alpha reductase selective inhibitor with steroid structure - azasteroid. Not an antiandrogen.

Mechanism:
MK386, reversibly inhibit type 1 of 5 alpha-reductas...click for details

LY 191704 - nonsteroidal inhibitor of 5a-reductase type I.

(8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octaahydro-benzo[f]quinol in-3(2H)-one)

New nonsteroidal inhibitor of 5 alpha-reductase type 1.

Mechanism:
LY191704 specifically bloc...click for details

SK&F 105657 - competitive inhibitor of 5a-reductase.

New competitive inhibitor of 5a-reductase. It is not an antiandrogen.

Mechanism:
SK&F 105657 blocks the peripheral conversion of testosterone to DHT by 5a-reductase in competitive mode, ...click for details

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